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Rabbit anti-Human NUTF2 Polyclonal Antibody

The antibody against NUTF2 was raised in rabbit using the Human NUTF2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47753A

The antibody against NUTF2 was raised in rabbit using the Human NUTF2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47753A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNUTF2
Target SynonymsNTF 2 antibody; NTF-2 antibody; NTF2 antibody; NTF2_HUMAN antibody; Nuclear transport factor 2 antibody; Nutf2 antibody; Placental protein 15 antibody; PP15 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NUTF2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP61970
Background Information
  • Uniprot Id

    P61970

  • Target Species

    Human

  • Target Name

    NUTF2

  • Target Full Name

    Nuclear transport factor 2

  • Target Function

    Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.

  • Target Subcellular Location

    Cytoplasm, cytosol. Nucleus outer membrane. Nucleus, nuclear pore complex. Nucleus inner membrane. Nucleus, nucleoplasm.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    NTF 2; NTF-2; NTF2; NTF2_HUMAN; Nuclear transport factor 2; Nutf2; Placental protein 15; PP15

  • Target Background

    This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62.

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