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The antibody against PDCL3 was raised in rabbit using the Recombinant Human Phosducin-like protein 3 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against PDCL3 was raised in rabbit using the Recombinant Human Phosducin-like protein 3 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-00773A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDCL3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosducin-like protein 3 protein (1-239AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2J4 |
Uniprot Id
Q9H2J4
Target Species
Human
Target Name
PDCL3
Target Full Name
Phosducin-like protein 3
Target Function
Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes. Modulates the activation of caspases during apoptosis.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Target Protein Families
Phosducin family
Target Tissue Specificity
Expressed in endothelial cells (at protein level). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.
Target Synonyms
HTPHLP; IAP associated factor VIAF1; MGC3062; PDCL 3; Pdcl3; PDCL3_HUMAN; PHLP2A; PHLP3; Phosducin like 3; Phosducin like protein 3; Phosducin-like protein 3; PhPL3; VIAF 1; VIAF; VIAF-1; VIAF1; Viral IAP associated factor 1; Viral IAP-associated factor 1
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