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The antibody against PDE4C was raised in rabbit using the Synthesized peptide derived from internal of Human PDE4C. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against PDE4C was raised in rabbit using the Synthesized peptide derived from internal of Human PDE4C. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from A549 cells, RAW264.7 cells and HuvEc cells, using PDE4C antibody.
| Cat.No | ADC-41386A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDE4C |
| Target Synonyms | cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila) antibody; Phosphodiesterase E1 dunce homolog antibody; Phosphodiesterase E1 dunce homolog Drosophila antibody; Phosphodiesterase type 4C antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PDE4C. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q08493 |
Uniprot Id
Q08493
Target Species
Human
Target Name
PDE4C
Target Full Name
3',5'-cyclic-AMP phosphodiesterase 4C
Target Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Target Subcellular Location
Cell projection, cilium.
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE4 subfamily
Target Tissue Specificity
Expressed in various tissues but not in cells of the immune system.
Target Synonyms
DPDE1; PDE21; PDE4C
Target Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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