Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against PDE6A was raised in rabbit using the Recombinant Human Rod cGMP-specific 3\',5\'-cyclic phosphodiesterase subunit alpha protein (656-860AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PDE6A was raised in rabbit using the Recombinant Human Rod cGMP-specific 3\’,5\’-cyclic phosphodiesterase subunit alpha protein (656-860AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using PDE6A Antibody at dilution of 1:1002
| Cat.No | ADC-16291A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDE6A |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rod cGMP-specific 3\',5\'-cyclic phosphodiesterase subunit alpha protein (656-860AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P16499 |
Uniprot Id
P16499
Target Species
Human
Target Name
PDE6A
Target Full Name
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Target Function
This protein participates in processes of transmission and amplification of the visual signal.
Target Involvement
Retinitis pigmentosa 43 (RP43)
Target Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.
Target Protein Families
Cyclic nucleotide phosphodiesterase family
Target Synonyms
PDEA; RP43; CGPR-A; PDE6A
Target Background
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
