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The antibody against PDE8B was raised in rabbit using the Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8Bprotein (18-110AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against PDE8B was raised in rabbit using the Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8Bprotein (18-110AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-02707A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDE8B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8Bprotein (18-110AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95263 |
Uniprot Id
O95263
Target Species
Human
Target Name
PDE8B
Target Full Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Target Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
Target Involvement
Striatal degeneration, autosomal dominant 1 (ADSD1); Primary pigmented nodular adrenocortical disease 3 (PPNAD3)
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE8 subfamily
Target Tissue Specificity
Abundantly expressed in the thyroid. Also very weakly expressed in brain, spinal cord and placenta. In the thyroid isoform 1 predominates, and isoforms 2 and 6 are also highly expressed. In the placenta isoforms 1 and 2 are expressed equally. In the brain
Target Synonyms
3' 5' cyclic nucleotide phosphodiesterase 8B; 3'5' cyclic nucleotide phosphodiesterase 8B ; Cell proliferation-inducing gene 22 protein; FLJ11212; High affinity cAMP specific and IBMX insensitive 3' 5' cyclic phosphodiesterase 8B; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8B; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; HSPDE 8B; HsPDE8B; PDE 8B; PDE8B; PDE8B_HUMAN; Phosphodiesterase 8B; Phosphodiesterase8B; PIG22
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