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The antibody against PGLYRP2 was raised in rabbit using the Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PGLYRP2 was raised in rabbit using the Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using PGLYRP2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using PGLYRP2 Antibody at dilution of 1:1002
| Cat.No | ADC-50190A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PGLYRP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96PD5 |
Uniprot Id
Q96PD5
Target Species
Human
Target Name
PGLYRP2
Target Full Name
N-acetylmuramoyl-L-alanine amidase
Target Function
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Target Subcellular Location
Secreted. Membrane.
Target Protein Families
N-acetylmuramoyl-L-alanine amidase 2 family
Target Tissue Specificity
Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.
Target Research Area
Immunology
Target Synonyms
PGLYRP2; PGLYRPL; PGRPL; UNQ3103/PRO10102; N-acetylmuramoyl-L-alanine amidase; EC 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L
Target Background
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments.
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