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Rabbit anti-Human Phospho-KCNJ16 (S416) Polyclonal Antibody

The antibody against Kcnj16 was raised in rabbit using the Synthesized peptide derived from Human KIR5.1 around the phosphorylation site of S416. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-36719A

The antibody against Kcnj16 was raised in rabbit using the Synthesized peptide derived from Human KIR5.1 around the phosphorylation site of S416. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-36719A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKCNJ16
Target SynonymsKcnj16 antibody; Inward rectifier potassium channel 16 antibody; Inward rectifier K(+) channel Kir5.1 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 16 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human KIR5.1 around the phosphorylation site of S416.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Z307
Background Information
  • Uniprot Id

    Q9Z307

  • Target Species

    Human

  • Target Name

    KCNJ16

  • Target Function

    Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein. Basolateral cell membrane.

  • Target Protein Families

    Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ16 subfamily

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