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The antibody against PMF1 was raised in rabbit using the Human PMF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against PMF1 was raised in rabbit using the Human PMF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47594A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PMF1 |
| Target Synonyms | NNF1R antibody; PMF 1 antibody; PMF-1 antibody; Pmf1 antibody; PMF1_HUMAN antibody; Polyamine modulated factor 1 antibody; Polyamine-modulated factor 1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PMF1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6P1K2 |
Uniprot Id
Q6P1K2
Target Species
Human
Target Name
PMF1
Target Full Name
Polyamine-modulated factor 1
Target Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
Target Subcellular Location
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Target Tissue Specificity
Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.
Target Synonyms
NNF1R; PMF 1; PMF-1; Pmf1; PMF1_HUMAN; Polyamine modulated factor 1; Polyamine-modulated factor 1
Target Background
Enables leucine zipper domain binding activity and transcription coactivator activity. Involved in chromosome segregation. Located in Golgi apparatus; kinetochore; and nucleoplasm. Part of MIS12/MIND type complex. Implicated in bladder carcinoma and urinary bladder cancer.
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