Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against PPP1R16B was raised in rabbit using the Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PPP1R16B was raised in rabbit using the Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human lung tissue using PPP1R16B Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using PPP1R16B Antibody at dilution of 1:1002
| Cat.No | ADC-18816A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPP1R16B |
| Target Synonyms | regulatory (inhibitor) subunit 16B antibody; TGF beta inhibited membrane associated protein antibody; TGF-beta-inhibited membrane-associated protein antibody; TIMAP antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96T49 |
Uniprot Id
Q96T49
Target Species
Human
Target Name
PPP1R16B
Target Full Name
Protein phosphatase 1 regulatory inhibitor subunit 16B
Target Function
Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation. Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity. Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the dephosphorylation of EEF1A1.
Target Subcellular Location
Cell membrane. Cell membrane; Lipid-anchor. Nucleus. Cell projection.
Target Synonyms
ANKRD4; Ankyrin repeat domain containing protein 4; ankyrin repeat domain protein 4; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; hTIMAP; KIAA0823; PP16B_HUMAN; PPP1R16B; Protein phosphatase 1 regulatory inhibitor subunit 16B; protein phosphatase 1, regulatory (inhibitor) subunit 16B; TGF beta inhibited membrane associated protein; TGF-beta-inhibited membrane-associated protein; TIMAP
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
