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The antibody against PREX1 was raised in rabbit using the Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PREX1 was raised in rabbit using the Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry analysis of human colon cancer using PREX1 Antibody at dilution of 1:100
Immunocytochemistry analysis of human lung tissue using PREX1 Antibody at dilution of 1:1002
Immunofluorescent analysis of MCF-7 cells using PREX1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-10189A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PREX1 |
| Target Synonyms | 4, 4 antibody; 5)-dependent Rac exchanger 1 antibody; KIAA1415 antibody; OTTHUMP00000031228 antibody; P REX1 antibody; P Rex1 protein like antibody; P-Rex1 antibody; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchange factor 1 antibody; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchanger 1 antibody; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchanger 1 protein antibody; Phosphatidylinositol 3, 5-trisphosphate-dependent Rac exchanger 1 protein antibody; Prex1 antibody; PREX1_HUMAN antibody; PtdIns(3 antibody; PtdIns(3, 5) dependent Rac exchanger 1 antibody; SET domain containing 6 antibody; Setd6 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TCU6 |
Uniprot Id
Q8TCU6
Target Species
Human
Target Name
PREX1
Target Full Name
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Target Function
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Target Subcellular Location
Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane.
Target Tissue Specificity
Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.
Target Synonyms
4; 5)-dependent Rac exchanger 1; KIAA1415; OTTHUMP00000031228; P REX1; P Rex1 protein like; P-Rex1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; Prex1; PREX1_HUMAN; PtdIns(3; PtdIns(3,4,5) dependent Rac exchanger 1; SET domain containing 6; Setd6
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