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The antibody against PROK2 was raised in rabbit using the Recombinant Human Prokineticin-2 protein (20-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against PROK2 was raised in rabbit using the Recombinant Human Prokineticin-2 protein (20-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using PROK2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using PROK2 Antibody at dilution of 1:1002
| Cat.No | ADC-17339A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PROK2 |
| Target Synonyms | BV8 antibody; Bv8 homolog antibody; MIT1 antibody; PK2 antibody; PROK2 antibody; PROK2_HUMAN antibody; Prokineticin-2 antibody; Protein Bv8 homolog antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Prokineticin-2 protein (20-129AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HC23 |
Uniprot Id
Q9HC23
Target Species
Human
Target Name
PROK2
Target Full Name
Prokineticin-2
Target Function
May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
Target Involvement
Hypogonadotropic hypogonadism 4 with or without anosmia (HH4)
Target Subcellular Location
Secreted.
Target Protein Families
AVIT (prokineticin) family
Target Tissue Specificity
Expressed in the testis and, at low levels, in the small intestine.
Target Synonyms
BV8; Bv8 homolog ; MIT1 ; PK2; PROK2; PROK2_HUMAN; Prokineticin-2; Protein Bv8 homolog
Target Background
This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
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