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The antibody against PROP1 was raised in rabbit using the Recombinant Human Homeobox protein prophet of Pit-1 protein (6-214AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PROP1 was raised in rabbit using the Recombinant Human Homeobox protein prophet of Pit-1 protein (6-214AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-12481A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PROP1 |
| Target Synonyms | PROP1 antibody; Homeobox protein prophet of Pit-1 antibody; PROP-1 antibody; Pituitary-specific homeodomain factor antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Homeobox protein prophet of Pit-1 protein (6-214AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75360 |
Uniprot Id
O75360
Target Species
Human
Target Name
PROP1
Target Full Name
Homeobox protein prophet of Pit-1
Target Function
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
Target Involvement
Pituitary hormone deficiency, combined, 2 (CPHD2)
Target Subcellular Location
Nucleus.
Target Protein Families
Paired homeobox family
Target Tissue Specificity
Expressed specifically in embryonic pituitary.
Target Synonyms
PROP1; Homeobox protein prophet of Pit-1; PROP-1; Pituitary-specific homeodomain factor
Target Background
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.
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