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The antibody against RANGRF was raised in rabbit using the Human RANGRF as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against RANGRF was raised in rabbit using the Human RANGRF as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47414A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RANGRF |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human RANGRF | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HD47 |
Uniprot Id
Q9HD47
Target Species
Human
Target Name
RANGRF
Target Full Name
Ran guanine nucleotide release factor
Target Function
May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics. Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.
Target Subcellular Location
Nucleus. Cytoplasm, perinuclear region. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
MOG1 family
Target Tissue Specificity
Isoform 1 and isoform 2 are ubiquitously expressed. Detected in heart and brain.
Target Synonyms
DKFZp686F02139; HSPC165; HSPC236; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; Ran guanine nucleotide release factor; Ran-binding protein MOG1; RanGNRF; RANGRF
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