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The antibody against RASSF6 was raised in rabbit using the Synthesized peptide derived from internal of Human RASSF6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against RASSF6 was raised in rabbit using the Synthesized peptide derived from internal of Human RASSF6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HeLa cells, using RASSF6 antibody.
| Cat.No | ADC-40982A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RASSF6 |
| Target Synonyms | RASSF6 antibody; Ras association domain-containing protein 6 antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human RASSF6. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZTQ3 |
Uniprot Id
Q6ZTQ3
Target Species
Human
Target Name
RASSF6
Target Full Name
Ras association domain-containing protein 6
Target Function
Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B.
Target Tissue Specificity
Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the n
Target Research Area
others
Target Synonyms
RASSF6; Ras association domain-containing protein 6
Target Background
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.
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