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Rabbit anti-Human REG3G Polyclonal Antibody

The antibody against REG3G was raised in rabbit using the Fusion protein of Human REG3G as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-29697A

The antibody against REG3G was raised in rabbit using the Fusion protein of Human REG3G as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-29697A ClonalityPolyclonal
Host SpeciesRabbitTarget NameREG3G
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human REG3GTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6UW15
Background Information
  • Uniprot Id

    Q6UW15

  • Target Species

    Human

  • Target Name

    REG3G

  • Target Full Name

    Regenerating islet-derived protein 3-gamma

  • Target Function

    Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.

  • Target Subcellular Location

    Secreted. Cytoplasm.

  • Target Tissue Specificity

    Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta.

  • Target Research Area

    Immunology

  • Target Synonyms

    LPPM429; Pancreatitis-associated protein 1B; Pancreatitis-associated protein IB; PAP IB; PAP-1B; PAP1B; PAPIB; REG III; Reg III-gamma; REG-3-gamma; REG3G; REG3G_HUMAN; Regenerating islet derived 3 gamma; Regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein III-gamma; UNQ429

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