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The antibody against RGS19 was raised in rabbit using the Recombinant Human Regulator of G-protein signaling 19 protein (1-87AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against RGS19 was raised in rabbit using the Recombinant Human Regulator of G-protein signaling 19 protein (1-87AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using RGS19 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using RGS19 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using RGS19 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-12457A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RGS19 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Regulator of G-protein signaling 19 protein (1-87AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49795 |
Uniprot Id
P49795
Target Species
Human
Target Name
RGS19
Target Full Name
Regulator of G-protein signaling 19
Target Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Target Subcellular Location
Membrane; Lipid-anchor.
Target Tissue Specificity
Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Target Synonyms
G alpha interacting protein; G protein signalling regulator 19; G protein; alpha-interacting protein; G-alpha-interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein ; Regulator of G protein signalling 19; Regulator of G-protein signaling 19; RGS19; RGS19_HUMAN; RGSGAIP
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