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Rabbit anti-Human RGS7 Polyclonal Antibody

The antibody against RGS7 was raised in rabbit using the Human RGS7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-52065A

The antibody against RGS7 was raised in rabbit using the Human RGS7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-52065A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRGS7
Target SynonymsRGS7 antibody; Regulator of G-protein signaling 7 antibody; RGS7 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman RGS7Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49802
Background Information
  • Uniprot Id

    P49802

  • Target Species

    Human

  • Target Name

    RGS7

  • Target Full Name

    Regulator of G-protein signaling 7

  • Target Function

    Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.

  • Target Subcellular Location

    Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    RGS7; Regulator of G-protein signaling 7; RGS7

  • Target Background

    Enables G-protein beta-subunit binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Located in cytosol.

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