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Rabbit anti-Human RMND5B Polyclonal Antibody, FITC conjugated

The antibody against RMND5B was raised in rabbit using the Recombinant Human Protein RMD5 homolog B protein (1-260AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-23825A

The antibody against RMND5B was raised in rabbit using the Recombinant Human Protein RMD5 homolog B protein (1-260AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-23825A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRMND5B
Target SynonymsRMND5B antibody; UNQ2508/PRO5996 antibody; E3 ubiquitin-protein transferase RMND5B antibody; EC 2.3.2.27 antibody; Protein RMD5 homolog B antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateFITC conjugatedStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein RMD5 homolog B protein (1-260AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96G75
Background Information
  • Uniprot Id

    Q96G75

  • Target Species

    Human

  • Target Name

    RMND5B

  • Target Full Name

    E3 ubiquitin-protein transferase RMND5B

  • Target Function

    Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.

  • Target Subcellular Location

    Cytoplasm, cytosol.

  • Target Synonyms

    RMND5B; UNQ2508/PRO5996; E3 ubiquitin-protein transferase RMND5B; EC 2.3.2.27; Protein RMD5 homolog B

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