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The antibody against RNASE3 was raised in rabbit using the Fusion protein of Human RNASE3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against RNASE3 was raised in rabbit using the Fusion protein of Human RNASE3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-30153A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RNASE3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human RNASE3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P12724 |
Uniprot Id
P12724
Target Species
Human
Target Name
RNASE3
Target Full Name
Eosinophil cationic protein
Target Function
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Target Subcellular Location
Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Target Protein Families
Pancreatic ribonuclease family
Target Synonyms
ECP; RAF1; RNS3; RNASE3
Target Background
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria
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