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Rabbit anti-Human RNF183 Polyclonal Antibody, FITC conjugated

The antibody against RNF183 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF183 protein (1-161AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-23803A

The antibody against RNF183 was raised in rabbit using the Recombinant Human E3 ubiquitin-protein ligase RNF183 protein (1-161AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-23803A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRNF183
Target SynonymsRNF183; E3 ubiquitin-protein ligase RNF183FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateFITC conjugatedStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human E3 ubiquitin-protein ligase RNF183 protein (1-161AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96D59
Background Information
  • Uniprot Id

    Q96D59

  • Target Species

    Human

  • Target Name

    RNF183

  • Target Full Name

    E3 ubiquitin-protein ligase RNF183

  • Target Function

    Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1. May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum. Golgi apparatus, cis-Golgi network membrane. Lysosome membrane.

  • Target Tissue Specificity

    Kidney and testis.

  • Target Synonyms

    RNF183; E3 ubiquitin-protein ligase RNF183

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