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The antibody against RPP25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RPP25 (NP_060263.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against RPP25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RPP25 (NP_060263.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-00837A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RPP25 |
| Target Synonyms | RPP25 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A375, HT-29 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RPP25 (NP_060263.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MENFRKVRSEEAPAGCGAEGGGPGSGPFADLAPGAVHMRVKEGSKIRNLMAFATASMAQPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSLPPGPTQGQTPGEPAASLSVLKNVPGLAILLSKDALDPRQPGYQPPNPHPGPSSPPAAPASKRSLGEPAAGEGSAKRSQPEPGVADEDQTA | Uniprot ID | Q9BUL9 |
Uniprot Id
Q9BUL9
Target Species
Human
Target Name
RPP25
Target Full Name
Ribonuclease P protein subunit p25
Target Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
Histone-like Alba family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
LJ20374; Ribonuclease P protein subunit p25; RNase P protein subunit p25; Rpp25; RPP25_HUMAN
Target Background
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in centriolar satellite and nucleoplasm. Part of multimeric ribonuclease P complex and ribonuclease MRP complex. Biomarker of autistic disorder.
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