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The antibody against RRAGB was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Rag B. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against RRAGB was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Rag B. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-36650A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RRAGB |
| Target Synonyms | RRAGB antibody; Ras-related GTP-binding protein B antibody; Rag B antibody; RagB antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Rag B. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VZM2 |
Uniprot Id
Q5VZM2
Target Species
Human
Target Name
RRAGB
Target Full Name
Ras-related GTP-binding protein B
Target Function
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Target Subcellular Location
Cytoplasm. Lysosome.
Target Protein Families
GTR/RAG GTP-binding protein family
Target Synonyms
RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
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