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The antibody against SGCE was raised in rabbit using the Recombinant Human Epsilon-sarcoglycan protein (8-126AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against SGCE was raised in rabbit using the Recombinant Human Epsilon-sarcoglycan protein (8-126AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-03429A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SGCE |
| Target Synonyms | SGCE; ESG; UNQ433/PRO840; Epsilon-sarcoglycan; Epsilon-SG | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Epsilon-sarcoglycan protein (8-126AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43556 |
Uniprot Id
O43556
Target Species
Human
Target Name
SGCE
Target Full Name
Epsilon-sarcoglycan
Target Function
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Target Involvement
Dystonia 11, myoclonic (DYT11)
Target Subcellular Location
Cell membrane, sarcolemma; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cell projection, dendrite. Golgi apparatus.
Target Protein Families
Sarcoglycan alpha/epsilon family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
SGCE; ESG; UNQ433/PRO840; Epsilon-sarcoglycan; Epsilon-SG
Target Background
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2.
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