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The antibody against SHANK1 was raised in rabbit using the Synthetic peptide of Human SHANK1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SHANK1 was raised in rabbit using the Synthetic peptide of Human SHANK1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-27490A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SHANK1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human SHANK1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y566 |
Uniprot Id
Q9Y566
Target Species
Human
Target Name
SHANK1
Target Full Name
SH3 and multiple ankyrin repeat domains protein 1
Target Function
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
Target Subcellular Location
Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
Target Protein Families
SHANK family
Target Tissue Specificity
Expressed in brain particularly in the amygdala, hippocampus, substantia nigra and thalamus. Isoform 2 seems to be expressed ubiquitously.
Target Synonyms
GKAP/SAPAP interacting protein; OTTHUMP00000174437; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHAN1_HUMAN; SHANK 1; Shank1; Shank1a; Somatostatin receptor interacting protein; Somatostatin receptor-interacting protein; SPANK 1; SPANK1; SSTR interacting protein; SSTR-interacting protein; SSTRIP; Synamon
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