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The antibody against SLC12A7 was raised in rabbit using the Recombinant Human Solute carrier family 12 member 7 protein (11-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC12A7 was raised in rabbit using the Recombinant Human Solute carrier family 12 member 7 protein (11-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human ovarian cancer using SLC12A7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using SLC12A7 Antibody at dilution of 1:1002
Immunofluorescent analysis of A549 cells using SLC12A7 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-09997A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC12A7 |
| Target Synonyms | member 7 antibody, member 7 antibody; Solute carrier family 12 member 7 antibody; Solute carrier family 12 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Solute carrier family 12 member 7 protein (11-117AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y666 |
Uniprot Id
Q9Y666
Target Species
Human
Target Name
SLC12A7
Target Full Name
Solute carrier family 12 member 7
Target Function
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
SLC12A transporter family
Target Tissue Specificity
Detected in muscle, brain, lung, heart and kidney.
Target Synonyms
KCC4; SLC12A7
Target Background
Enables protein kinase binding activity. Predicted to be involved in several processes, including cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Part of protein-containing complex.
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