Rabbit anti-Human SLC27A6 Polyclonal Antibody

Uniprot Id

Q9Y2P4

Target Species

Human

Target Name

SLC27A6

Target Full Name

Long-chain fatty acid transport protein 6

Target Function

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs).

Target Subcellular Location

Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Target Protein Families

ATP-dependent AMP-binding enzyme family

Target Tissue Specificity

Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus.

Target Synonyms

SLC27A6; ACSVL2; FACVL2; FATP6; Long-chain fatty acid transport protein 6; FATP-6; Fatty acid transport protein 6; Arachidonate--CoA ligase; Fatty-acid-coenzyme A ligase, very long-chain 2; Solute carrier family 27 member 6; Very long-chain acyl-CoA synthetase homolog 1; VLCSH1; hVLCS-H1

Target Background

This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene.