Rabbit anti-Human SLC2A8 Polyclonal Antibody

Uniprot Id

Q9NY64

Target Species

Human

Target Name

SLC2A8

Target Full Name

Solute carrier family 2, facilitated glucose transporter member 8

Target Function

Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate.

Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Target Protein Families

Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily

Target Tissue Specificity

Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.

Target Synonyms

SLC2A8; GLUT8; GLUTX1; Solute carrier family 2; facilitated glucose transporter member 8; Glucose transporter type 8; GLUT-8; Glucose transporter type X1

Target Background

This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene.