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The antibody against SLC44A4 was raised in rabbit using the Recombinant Human Choline transporter-like protein 4 protein (56-229AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against SLC44A4 was raised in rabbit using the Recombinant Human Choline transporter-like protein 4 protein (56-229AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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Immunofluorescent analysis of Hela cells using SLC44A4 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-40031A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC44A4 |
| Target Synonyms | C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Choline transporter-like protein 4 protein (56-229AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53GD3 |
Uniprot Id
Q53GD3
Target Species
Human
Target Name
SLC44A4
Target Full Name
Choline transporter-like protein 4
Target Function
Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury. Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis.; Has also thiamine pyrophosphate transporter activity.
Target Involvement
Deafness, autosomal dominant, 72 (DFNA72)
Target Subcellular Location
Membrane; Multi-pass membrane protein. Apical cell membrane.
Target Protein Families
CTL (choline transporter-like) family
Target Tissue Specificity
Highly expressed in colon, also detected in prostate, trachea and lung. Isoform 3 is also expressed in colon but a lower levels.
Target Research Area
Others
Target Synonyms
C6orf29; Choline transporter-like protein 4; CTL4; CTL4_HUMAN; NG22; Slc44a4; Solute carrier family 44 member 4; UNQ441/PRO874
Target Background
The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene.
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