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The antibody against SLC5A2 was raised in rabbit using the Recombinant Human Sodium/glucose cotransporter 2 protein (335-422AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLC5A2 was raised in rabbit using the Recombinant Human Sodium/glucose cotransporter 2 protein (335-422AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using SLC5A2 Antibody at dilution of 1:100
Immunofluorescent analysis of A549 cells using SLC5A2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-21411A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC5A2 |
| Target Synonyms | SLC5A2; SGLT2; Sodium/glucose cotransporter 2; Na(+/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium/glucose cotransporter 2 protein (335-422AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P31639 |
Uniprot Id
P31639
Target Species
Human
Target Name
SLC5A2
Target Full Name
Sodium/glucose cotransporter 2
Target Function
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
Target Involvement
Renal glucosuria (GLYS)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:solute symporter (SSF) (TC 2.A.21) family
Target Research Area
Signal Transduction
Target Synonyms
SLC5A2; SGLT2; Sodium/glucose cotransporter 2; Na(+/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
Target Background
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene.
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