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The antibody against SLC6A6 was raised in rabbit using the Synthesized peptide derived from internal of Human SC6A6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against SLC6A6 was raised in rabbit using the Synthesized peptide derived from internal of Human SC6A6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from COLO205 cells, using SC6A6 antibody.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SC6A6 antibody.2
| Cat.No | ADC-40903A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A6 |
| Target Synonyms | member 6 antibody; Solute carrier family 6 member 6 antibody; TAUT antibody, taurine) | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human SC6A6. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P31641 |
Uniprot Id
P31641
Target Species
Human
Target Name
SLC6A6
Target Full Name
Sodium- and chloride-dependent taurine transporter
Target Function
Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A6 subfamily
Target Tissue Specificity
Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
Target Synonyms
MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6_HUMAN; SLC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 (neurotransmitter transporter, taurine), member 6; Solute carrier family 6 member 6; TAUT
Target Background
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants.
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