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The antibody against SMS was raised in rabbit using the Recombinant Human Spermine synthase protein (16-191AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SMS was raised in rabbit using the Recombinant Human Spermine synthase protein (16-191AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human prostate cancer using SMS Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using SMS Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using SMS Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-14537A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Spermine synthase protein (16-191AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P52788 |
Uniprot Id
P52788
Target Species
Human
Target Name
SMS
Target Full Name
Spermine synthase
Target Function
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
Target Involvement
X-linked syndromic mental retardation Snyder-Robinson type (MRXSSR)
Target Protein Families
Spermidine/spermine synthase family
Target Synonyms
MRSR; SMS; Snyder Robinson X linked mental retardation syndrome; Spermidine aminopropyltransferase; Spermine synthase; SPMSY; SpS; SPSY_HUMAN; SRS
Target Background
This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene.
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