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The antibody against SPAG9 was raised in rabbit using the Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 protein (209-259AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SPAG9 was raised in rabbit using the Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 protein (209-259AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human melanoma using SPAG9 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using SPAG9 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using SPAG9 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-15689A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPAG9 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 protein (209-259AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60271 |
Uniprot Id
O60271
Target Species
Human
Target Name
SPAG9
Target Full Name
C-Jun-amino-terminal kinase-interacting protein 4
Target Function
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Lysosome membrane.; [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome.
Target Protein Families
JIP scaffold family
Target Tissue Specificity
Expressed only in testis on the round spermatids of stage I, II and II. Absent in spermatogonia and spermatocyte.; [Isoform 4]: Expressed in testis and in acute myeloid leukemia (AML) patients.; [Isoform 3]: Expressed in testis.
Target Research Area
Developmental Biology
Target Synonyms
SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6C-Jun-amino-terminal kinase-interacting protein 4; JIP-4; JNK-interacting protein 4; Cancer/testis antigen 89; CT89; Human lung cancer oncogene 6 protein; HLC-6; JNK-associated leucine-zipper protein; JLP; Mitogen-activated protein kinase 8-interacting protein 4; Proliferation-inducing protein 6; Protein highly expressed in testis; PHET; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1
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