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Rabbit anti-Human SPC25 Polyclonal Antibody

The antibody against SPC25 was raised in rabbit using the Recombinant Human Kinetochore protein Spc25 protein (1-224AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-18039A

The antibody against SPC25 was raised in rabbit using the Recombinant Human Kinetochore protein Spc25 protein (1-224AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-18039A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSPC25
Target SynonymsAD024 antibody; hSpc25 antibody; Kinetochore protein Spc25 antibody; SPBC25 antibody; SPC25 antibody; SPC25_HUMAN antibody; spindle pole body component 25 homolog antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Kinetochore protein Spc25 protein (1-224AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9HBM1
Background Information
  • Uniprot Id

    Q9HBM1

  • Target Species

    Human

  • Target Name

    SPC25

  • Target Full Name

    Kinetochore protein Spc25

  • Target Function

    Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.

  • Target Subcellular Location

    Nucleus. Chromosome, centromere, kinetochore.

  • Target Protein Families

    SPC25 family

  • Target Synonyms

    AD024; hSpc25; Kinetochore protein Spc25; SPBC25; SPC25; SPC25_HUMAN; spindle pole body component 25 homolog

  • Target Background

    This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity.

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