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The antibody against SPRR1B was raised in rabbit using the Recombinant Human Cornifin-B protein (1-89AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SPRR1B was raised in rabbit using the Recombinant Human Cornifin-B protein (1-89AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skin tissue using SPRR1B Antibody at dilution of 1:100
| Cat.No | ADC-21377A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPRR1B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cornifin-B protein (1-89AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P22528 |
Uniprot Id
P22528
Target Species
Human
Target Name
SPRR1B
Target Full Name
Cornifin-B
Target Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Cornifin (SPRR) family
Target Tissue Specificity
Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
Target Synonyms
14.9 kDa pancornulin; Cornifin ; Cornifin B; Cornifin-B; CornifinB; GADD33; MGC61901; Small proline rich protein IB; Small proline-rich protein IB; SPR-IB; SPR1B_HUMAN; SPRIB; SPRR1; SPRR1B
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