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Rabbit anti-Human STMN2 Polyclonal Antibody

The antibody against STMN2 was raised in rabbit using the Recombinant Human Stathmin-2 protein (61-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-11694A

The antibody against STMN2 was raised in rabbit using the Recombinant Human Stathmin-2 protein (61-129AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-11694A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSTMN2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Stathmin-2 protein (61-129AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ93045
Background Information
  • Uniprot Id

    Q93045

  • Target Species

    Human

  • Target Name

    STMN2

  • Target Full Name

    Stathmin-2

  • Target Function

    Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium.

  • Target Protein Families

    Stathmin family

  • Target Tissue Specificity

    Neuron specific.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    Neuron specific growth associated protein; Neuronal growth associated protein; Neuronal growth associated protein (silencer element); Protein SCG10; SCG 10; SCG10; SCG10 protein; SCGN 10; SCGN10; SGC 10; SGC10; Stathmin 2; Stathmin like 2; Stathmin-2; STMN 2; STMN2; STMN2_HUMAN; Superior cervical ganglia neural specific 10; Superior cervical ganglion 10 protein; Superior cervical ganglion-10 protein; Superiorcervical ganglia neural specific 10

  • Target Background

    This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

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