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The antibody against TBX4 was raised in rabbit using the Recombinant Human T-box transcription factor TBX4 protein (355-511AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against TBX4 was raised in rabbit using the Recombinant Human T-box transcription factor TBX4 protein (355-511AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-04211A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBX4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human T-box transcription factor TBX4 protein (355-511AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57082 |
Uniprot Id
P57082
Target Species
Human
Target Name
TBX4
Target Full Name
T-box transcription factor TBX4
Target Function
Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.
Target Involvement
Ischiocoxopodopatellar syndrome (ICPPS)
Target Subcellular Location
Nucleus.
Target Synonyms
SPS; T box 4 ; T box protein 4; T box transcription factor TBX 4; T box transcription factor TBX4; T-box protein 4; T-box transcription factor TBX4; TBX 4; TBX4; TBX4_HUMAN
Target Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.
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