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The antibody against TCN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TCN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11105A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TCN1 |
| Target Synonyms | HC; TC1; TCI; TC-1; TCN1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | BT-474, HT-29 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P20061 | Immunogen Sequence |
Uniprot Id
P20061
Target Species
Human
Target Name
TCN1
Target Full Name
Transcobalamin-1
Target Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Target Subcellular Location
Secreted.
Target Protein Families
Eukaryotic cobalamin transport proteins family
Target Tissue Specificity
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Target Research Area
Signal Transduction
Target Synonyms
Haptocorin; Haptocorrin; HC; OTTHUMP00000235879; TC 1; TC I; TC-1; TC1; TCI; TCN 1; TCN1; TCO1_HUMAN; Transcobalamin 1; Transcobalamin I; Transcobalamin-1; Transcobalamin1; TranscobalaminI; Vitamin B12 binding protein; Vitamin B12 binding protein R binder family
Target Background
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
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