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Rabbit anti-Human TCN1 Polyclonal Antibody

The antibody against TCN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11105A

The antibody against TCN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11105A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTCN1
Target SynonymsHC; TC1; TCI; TC-1; TCN1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesBT-474, HT-29ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2).Target SpeciesHuman
Uniprot IDP20061Immunogen Sequence
Background Information
  • Uniprot Id

    P20061

  • Target Species

    Human

  • Target Name

    TCN1

  • Target Full Name

    Transcobalamin-1

  • Target Function

    Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Eukaryotic cobalamin transport proteins family

  • Target Tissue Specificity

    Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Haptocorin; Haptocorrin; HC; OTTHUMP00000235879; TC 1; TC I; TC-1; TC1; TCI; TCN 1; TCN1; TCO1_HUMAN; Transcobalamin 1; Transcobalamin I; Transcobalamin-1; Transcobalamin1; TranscobalaminI; Vitamin B12 binding protein; Vitamin B12 binding protein R binder family

  • Target Background

    This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.

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