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The antibody against TELO2 was raised in rabbit using the Human TELO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against TELO2 was raised in rabbit using the Human TELO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-51621A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TELO2 |
| Target Synonyms | CLK2 antibody; hCLK2 antibody; KIAA0683 antibody; Protein clk-2 homolog antibody; TEL2 antibody; TEL2 telomere maintenance 2 homolog antibody; TEL2, homolog antibody; telo2 antibody; TELO2_HUMAN antibody; Telomere length regulation protein TEL2 homolog antibody; Telomere maintenance 2 antibody, telomere maintenance 2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TELO2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4R8 |
Uniprot Id
Q9Y4R8
Target Species
Human
Target Name
TELO2
Target Full Name
Telomere length regulation protein TEL2 homolog
Target Function
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Target Involvement
You-Hoover-Fong syndrome (YHFS)
Target Subcellular Location
Cytoplasm. Membrane. Nucleus. Chromosome, telomere.
Target Protein Families
TEL2 family
Target Synonyms
CLK2; hCLK2; KIAA0683; Protein clk-2 homolog; TEL2; TEL2 telomere maintenance 2 homolog; TEL2, telomere maintenance 2, homolog; telo2; TELO2_HUMAN; Telomere length regulation protein TEL2 homolog; Telomere maintenance 2
Target Background
This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.
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