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Rabbit anti-Human TELO2 Polyclonal Antibody

The antibody against TELO2 was raised in rabbit using the Human TELO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-51621A

The antibody against TELO2 was raised in rabbit using the Human TELO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-51621A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTELO2
Target SynonymsCLK2 antibody; hCLK2 antibody; KIAA0683 antibody; Protein clk-2 homolog antibody; TEL2 antibody; TEL2 telomere maintenance 2 homolog antibody; TEL2, homolog antibody; telo2 antibody; TELO2_HUMAN antibody; Telomere length regulation protein TEL2 homolog antibody; Telomere maintenance 2 antibody, telomere maintenance 2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman TELO2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y4R8
Background Information
  • Uniprot Id

    Q9Y4R8

  • Target Species

    Human

  • Target Name

    TELO2

  • Target Full Name

    Telomere length regulation protein TEL2 homolog

  • Target Function

    Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

  • Target Involvement

    You-Hoover-Fong syndrome (YHFS)

  • Target Subcellular Location

    Cytoplasm. Membrane. Nucleus. Chromosome, telomere.

  • Target Protein Families

    TEL2 family

  • Target Synonyms

    CLK2; hCLK2; KIAA0683; Protein clk-2 homolog; TEL2; TEL2 telomere maintenance 2 homolog; TEL2, telomere maintenance 2, homolog; telo2; TELO2_HUMAN; Telomere length regulation protein TEL2 homolog; Telomere maintenance 2

  • Target Background

    This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.

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