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The antibody against THAP4 was raised in rabbit using the Fusion protein of Human THAP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against THAP4 was raised in rabbit using the Fusion protein of Human THAP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-29146A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | THAP4 |
| Target Synonyms | THAP4 antibody; CGI-36 antibody; PP238 antibody; THAP domain-containing protein 4 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human THAP4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WY91 |
Uniprot Id
Q8WY91
Target Species
Human
Target Name
THAP4
Target Full Name
Peroxynitrite isomerase THAP4
Target Function
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo, possibly modulating the transcriptional activity residing in the N-terminal region.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Synonyms
THAP4; CGI-36; PP238; THAP domain-containing protein 4
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