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The antibody against UBE3C was raised in rabbit using the Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against UBE3C was raised in rabbit using the Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-11345A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBE3C |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15386 |
Uniprot Id
Q15386
Target Species
Human
Target Name
UBE3C
Target Full Name
Ubiquitin-protein ligase E3C
Target Function
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
Target Synonyms
HectH2; KIAA0010; KIAA10; Ube3c; UBE3C_HUMAN; Ubiquitin protein isopeptide ligase (E3); Ubiquitin protein ligase E3C; Ubiquitin-protein ligase E3C
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