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The antibody against VPS50 was raised in rabbit using the Recombinant Human Syndetin protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against VPS50 was raised in rabbit using the Recombinant Human Syndetin protein (1-250AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human melanoma using VPS50 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using VPS50 Antibody at dilution of 1:1002
| Cat.No | ADC-18526A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VPS50 |
| Target Synonyms | VPS50 antibody; CCDC132 antibody; KIAA1861 antibody; Syndetin antibody; Coiled-coil domain-containing protein 132 antibody; EARP/GARPII complex subunit VPS50 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Syndetin protein (1-250AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96JG6 |
Uniprot Id
Q96JG6
Target Species
Human
Target Name
VPS50
Target Full Name
Syndetin
Target Function
Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Target Subcellular Location
Recycling endosome. Membrane.
Target Protein Families
Syndetin family
Target Tissue Specificity
Ubiquitous, with higher expression in brain and skeletal muscle.
Target Synonyms
VPS50; CCDC132; KIAA1861; Syndetin; Coiled-coil domain-containing protein 132; EARP/GARPII complex subunit VPS50
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