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The antibody against WDR59 was raised in rabbit using the Recombinant Human GATOR complex protein WDR59 protein (619-862AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against WDR59 was raised in rabbit using the Recombinant Human GATOR complex protein WDR59 protein (619-862AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-01463A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR59 |
| Target Synonyms | WDR59 antibody; KIAA1923 antibody; FP977 antibody; GATOR complex protein WDR59 antibody; WD repeat-containing protein 59 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GATOR complex protein WDR59 protein (619-862AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PJI9 |
Uniprot Id
Q6PJI9
Target Species
Human
Target Name
WDR59
Target Full Name
GATOR2 complex protein WDR59
Target Function
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
Target Subcellular Location
Lysosome membrane.
Target Protein Families
WD repeat WDR59 family
Target Synonyms
WDR59; KIAA1923; FP977; GATOR complex protein WDR59; WD repeat-containing protein 59
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