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The antibody against YAF2 was raised in rabbit using the Recombinant Human YY1-associated factor 2 protein (1-204AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against YAF2 was raised in rabbit using the Recombinant Human YY1-associated factor 2 protein (1-204AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using YAF2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using YAF2 Antibody at dilution of 1:1002
| Cat.No | ADC-19294A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YAF2 |
| Target Synonyms | MGC41856 antibody; YAF2 antibody; YAF2_HUMAN antibody; YY1-associated factor 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human YY1-associated factor 2 protein (1-204AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IY57 |
Uniprot Id
Q8IY57
Target Species
Human
Target Name
YAF2
Target Full Name
YY1-associated factor 2
Target Function
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
Target Subcellular Location
Nucleus.
Target Synonyms
MGC41856; YAF2; YAF2_HUMAN; YY1-associated factor 2
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