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Rabbit anti-Mus musculus (Mouse) Flii Polyclonal Antibody

The antibody against Flii was raised in rabbit using the Recombinant Mouse Protein flightless-1 homolog protein (495-827AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-49941A

The antibody against Flii was raised in rabbit using the Recombinant Mouse Protein flightless-1 homolog protein (495-827AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-49941A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFLII
Target SynonymsFlii antibody; Fli1 antibody; FliihProtein flightless-1 homolog antibodyFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse Protein flightless-1 homolog protein (495-827AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9JJ28
Background Information
  • Uniprot Id

    Q9JJ28

  • Target Species

    Mouse

  • Target Name

    FLII

  • Target Full Name

    Protein flightless-1 homolog

  • Target Function

    May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Essential for early embryonic development. May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.

  • Target Subcellular Location

    Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, focal adhesion. Note=Colocalizes to actin-rich structures in blastocysts and, together with HRAS, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes.

  • Target Tissue Specificity

    Expressed in blastocyst.

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