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The antibody against Has2 was raised in rabbit using the Recombinant Mouse Hyaluronan synthase 2 protein (67-374AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Has2 was raised in rabbit using the Recombinant Mouse Hyaluronan synthase 2 protein (67-374AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-49818A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAS2 |
| Target Synonyms | Has2 antibody; Hyaluronan synthase 2 antibody; EC 2.4.1.212 antibody; Hyaluronate synthase 2 antibody; Hyaluronic acid synthase 2 antibody; HA synthase 2 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Hyaluronan synthase 2 protein (67-374AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P70312 |
Uniprot Id
P70312
Target Species
Mouse
Target Name
HAS2
Target Full Name
Hyaluronan synthase 2
Target Function
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
NodC/HAS family
Target Tissue Specificity
Expressed in heart, brain, spleen, lung and skeletal muscle.
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