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Rabbit anti-Mus musculus (Mouse) Map3k1 Polyclonal Antibody

The antibody against Map3k1 was raised in rabbit using the Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-46453A

The antibody against Map3k1 was raised in rabbit using the Recombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-46453A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMAP3K1
FormLiquidSpecies ReactivityMouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse Mitogen-activated protein kinase kinase kinase 1 protein (1216-1493AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP53349
Background Information
  • Uniprot Id

    P53349

  • Target Species

    Mouse

  • Target Name

    MAP3K1

  • Target Full Name

    Mitogen-activated protein kinase kinase kinase 1

  • Target Function

    Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

  • Target Protein Families

    Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily

  • Target Tissue Specificity

    Highly expressed in the heart and spleen while a lower level expression is seen in the liver.

  • Target Research Area

    Others

  • Target Synonyms

    Map3k1; Mekk; Mekk1; Mitogen-activated protein kinase kinase kinase 1; EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1

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