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The antibody against Smox was raised in rabbit using the Recombinant Mouse Spermine oxidase protein (1-555AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Smox was raised in rabbit using the Recombinant Mouse Spermine oxidase protein (1-555AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-21395A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMOX |
| Target Synonyms | Smox antibody; SmoSpermine oxidase antibody; EC 1.5.3.16 antibody; Polyamine oxidase 1 antibody; PAO-1 antibody; PAOh1 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Spermine oxidase protein (1-555AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99K82 |
Uniprot Id
Q99K82
Target Species
Mouse
Target Name
SMOX
Target Full Name
Spermine oxidase
Target Function
Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Target Subcellular Location
Cytoplasm.; [Isoform 2]: Cytoplasm. Nucleus.
Target Protein Families
Flavin monoamine oxidase family
Target Tissue Specificity
Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
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