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Rabbit anti-Mus musculus (Mouse) Wnt3 Polyclonal Antibody

The antibody against Wnt3 was raised in rabbit using the Recombinant Mouse Proto-oncogene Wnt-3 protein (22-355AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-22951A

The antibody against Wnt3 was raised in rabbit using the Recombinant Mouse Proto-oncogene Wnt-3 protein (22-355AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-22951A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWnt3
Target SynonymsWnt3 antibody; Int-4 antibody; Wnt-3 antibody; Proto-oncogene Wnt-3 antibody; Proto-oncogene Int-4 antibodyFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse Proto-oncogene Wnt-3 protein (22-355AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP17553
Background Information
  • Uniprot Id

    P17553

  • Target Species

    Mouse

  • Target Name

    WNT3

  • Target Full Name

    Proto-oncogene Wnt-3

  • Target Function

    Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge and for normal embryonic limb development.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Secreted.

  • Target Protein Families

    Wnt family

  • Target Tissue Specificity

    Detected at low levels in adult brain. Dorsal portion of the neural tube, dorsal ectoderm, the branchial arches, and the limb buds.

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