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The antibody against C5 was raised in rabbit using the Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against C5 was raised in rabbit using the Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using C5 Antibody at dilution of 1:10
| Cat.No | ADC-50583A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C5 |
| Target Synonyms | C5 antibody; Complement C5a anaphylatoxin antibody | Form | Liquid |
| Species Reactivity | Pig | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA) | Target Species | Pig |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01032 |
Uniprot Id
P01032
Target Species
Pig
Target Name
C5
Target Function
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Target Subcellular Location
Secreted.
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