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Rabbit Exendin-4 Polyclonal Antibody

The antibody against Exendin-4 was raised in rabbit using the Synthetic peptide of Heloderma suspectum Exendin 4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.

ADC-26750A

The antibody against Exendin-4 was raised in rabbit using the Synthetic peptide of Heloderma suspectum Exendin 4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-26750A ClonalityPolyclonal
Host SpeciesRabbitTarget NameExendin-4
Target SynonymsExendin-4 antibody; Exenatide antibodyFormLiquid
Species ReactivityHeloderma suspectumIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Heloderma suspectum Exendin 4Target SpeciesHeloderma suspectum (Gila monster)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP26349
Background Information
  • Uniprot Id

    P26349

  • Target Species

    Heloderma suspectum (Gila monster)

  • Target Function

    Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Glucagon family

  • Target Tissue Specificity

    Expressed by the venom gland.

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